- Title
- Hepatitis B-related hepatocellular carcinoma: surveillance strategy directed by immune-epidemiology
- Creator
- Anugwom, Chimaobi M.; Allaire, Manon; Akbar, Sheikh Mohammad Fazle; Sultan, Amir; Bollipo, Steven; Mattos, Angelo Z.; Debes, Jose D.
- Relation
- Hepatoma Research Vol. 7, Issue 23
- Publisher Link
- http://dx.doi.org/10.20517/2394-5079.2021.06
- Publisher
- OAE Publishing
- Resource Type
- journal article
- Date
- 2021
- Description
- Hepatitis B infection (HBV) is one of the most common causes of hepatocellular carcinoma (HCC) worldwide. The age of occurrence, prognosis and incidence vary dramatically depending on the region of the world. This geographic variation is largely dependent on the contrasting incidence of HBV, age of transmission of the virus, the timing of integration into the human genome, and different HBV genotypes, as well as environmental factors. It results in a wide difference in viral interaction with the immune system, genomic modulation and the consequent development of HCC in an individual. In this review, we describe many factors implicated in HCC development, provide insight regarding at-risk populations and explain societal recommendations for HCC surveillance in persons living with HBV in different continents of the world.
- Subject
- HCC; HBV; continent; risk; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1456461
- Identifier
- uon:45224
- Identifier
- ISSN:2394-5079
- Rights
- © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- Language
- eng
- Full Text
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